IVF (In Vitro
IVF or Invitro
Fertilization (or tube baby) is the process of
facilitating fertilization out of the human body, where
fertilization is the act of the sperm
penetrating the ovum, and "invitro" means
"out of the human body". This option is resorted to whenever there
are obstacles for the in-body fertilization, such as weak sperm
motility, among other causes of infertility.
The process starts by induction of
ovulation. This is enhancement and stimulation of the female's ovary to produce
more ova than usual. Usually, ladies produce one ovum every month. Special
medications are given to the lady throughout one month that allow her to produce
more than one ovum, up to 30 ova in some cases. The progress of ovulation
(production of the ovum) is monitored every week by ultrasound and hormone
level measurement. These medications have no side effects apart from some
temporary water retention in rare cases. The production of a large number of
ova at once has no side effect on the lady's future fertility, since females
enter menopause having used only 40% of their ova. The rest is wasted.
When the ova are ready, they are
extracted out of the lady's ovum by a tiny needle that is inserted into the
ovary without pain (under anesthesia). Introduction of the needle is guided by
ultrasound. This is called "ovum pickup".
In the same day, fertilization occurs
by injecting sperm from the husband into the ova. Only one live sperm is
required for each ovum. This is called Intracytoplasmic sperm injection (ICSI).
ICSI differs from regular IVF in that the sperm is injected into the ovum
directly (ICSI) rather than left with the ovum for some time in a tight space
hoping fertilization will occur (IVF).
The injected ova are observed for 48
hours, and those that turn into embryos are immediately transferred back to the
lady's uterus, by painless injection. Since many embryos are usually injected,
the probability of twin and triplet pregnancy is higher than normal.
A pregnancy test should be performed
after 3 weeks. Pregnancy occurs in 35-45% of cases. If it does not, the process
can be repeated. Children born to IVF / ICSI are completely normal. There
is not a higher probability of congenital abnormalities in ICSI babies as
compared to those of natural conception.
Thus, IVF / ICSI can achieve conception
even in the most severe cases of infertility. For example:
Very few sperm? ICSI only needs one
sperm for each child
No sperm at all? Sperm can be
extracted from the testis and used in ICSI
Sperm does not move? ICSI does not
require the sperm to move (provided it is alive)
No ovum? The medications used to
stimulate ovulation can override this problem
The lady's fallopian tubes are
obstructed? ICSI extracts the ovum directly from the ovary without the need
for passage though the tubes.
In intrauterine insemination,
fertilization occurs inside the uterus. Ovulation is stimulated by medications,
and when the ova are ready, semen is prepared so as to purify sperm from
possible harmful materials in the seminal fluid, and is injected into the
uterus, so as to shorten the distance sperm have to travel to reach the ovum.
Fertilization occurs normally.
For IUI to succeed, it needs a minimum
of 4 million highly motile sperm, and it needs the tubes to be patent. Success
rate of IUI is about 15%.
/ ICSI in Egypt
IVF / ICSI in Egypt meets the highest
international standards. Kamal Shaeer Hospital is one
of the best IVF centers in Egypt, founded 1996 in collaboration with Nottingham
University, UK. It is recognized by the World Health Organization as a teaching
and directing center for physicians in the field. The center has expanded to
Luxor (Southern Egypt) and to United Arab Emirates (Sharjah).
In our centers, IVF / ICSI cost around
4000 USD. It is mandatory to stay in Egypt for 21 to 30 days, which is one more
reason to have this procedure performed in Egypt
During this period, it is possible to
enjoy the fabulous tourist attractions in Egypt, from those of the Ancient
Egyptian Civilization to the fascinating Red Sea, including visits to the
Pyramids, Egyptian museum, Nile cruises, Red Sea coral dives..endless amusement.
Another option is to have the procedure
done in the United Arab Emirates, 30 minutes from Dubai, one of the most famous,
advanced and booming World's markets, where refined shopping and entertainment
are at their very best.
Our centers can arrange for
accommodation and sight seeing in addition to the procedure.