The mechanism of erection
to be discussed here assumes that normal masculine development has
occurred at puberty by the correct balance between genes and
hormones.
1-The Nervous System
The brain exerts the main
control over sexual behavior. Special chemicals (neurotransmitters)
are present in the brain, some stimulatory for sexual behavior and
some inhibitory. At base line, the brain is under inhibitory effect
by day and stimulatory effect at sleep.
Sexual stimulation may be
sensory, by touch, visual, auditory, olfactory or imaginary
(fantasies). Sensory stimuli (touch) reach the brain from the penis
and skin through nerves then up the spinal cord. All of those
stimuli converge on the brain to induce the release of more
stimulatory neurotransmitters.
The released
neurotransmitters fire impulses down the spinal cord, then across
the peripheral nerves to the penis.
2-The Penis
Nerve impulses reach the
penis via the "pudendal" nerve. The impulses induce
neurotransmitters in the penis that start the cascade of events that
cause erection. Nitric oxide (NO) is the neurotransmitter that
is most important for erection.
Nitric oxide (NO)
induces dilatation (opening up) of arteries that pump blood at high
speed and large volumes into the
sinusoidal spaces of the
penis. "NO" also induces those spaces to dilate by
relaxing the
sinusoidal muscles that
surround them, thus accommodating the pumped blood inside the
corpora cavernosa which
are the two longitudinal cylinders spanning the length of the penis
and responsible for erection . The penis expands due to the large
volume of blood being pumped in. The
veins become compressed
against the inner wall of the
corpora cavernosa. Being
the outlet of blood, the compressed veins prevent blood from leaving
the penis. Gradually, blood volume and pressure increase inside the
corpora cavernosa leading to rigidity of the penis. Rigidity becomes
maximum when a muscle surrounding the base of the penis (bulbocavernosus)
contracts, tightening the blood filled penis and increasing blood
pressure within.
Nitric oxide (NO) is broken down and degraded by and enzyme
named "phosphodiesterase inhibitor" or (PDE)